International Journal of Drug Policy
Volume 21, Issue 4 , Pages 296-301 , July 2010

Drug use and the risk of HIV infection amongst injection drug users participating in an HIV vaccine trial in Bangkok, 1999–2003

  • Michael Martin

      Affiliations

    • Thailand Ministry of Public Health—U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand
    • Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States
    • Corresponding Author InformationCorresponding author at: DDC 7 Building, 4th Floor, Ministry of Public Health, Soi 4, Nonthaburi 11000, Thailand. Tel.: +66 2 580 0669; fax: +66 2 580 0712.
    • ,
  • Suphak Vanichseni

      Affiliations

    • Bangkok Vaccine Evaluation Group, Bangkok, Thailand
    • ,
  • Pravan Suntharasamai

      Affiliations

    • Mahidol University, Bangkok, Thailand
    • ,
  • Philip A. Mock

      Affiliations

    • Thailand Ministry of Public Health—U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand
    • ,
  • Frits van Griensven

      Affiliations

    • Thailand Ministry of Public Health—U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand
    • Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States
    • ,
  • Punnee Pitisuttithum

      Affiliations

    • Mahidol University, Bangkok, Thailand
    • ,
  • Jordan W. Tappero

      Affiliations

    • Thailand Ministry of Public Health—U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand
    • Global AIDS Program, Centers for Disease Control and Prevention, Atlanta, GA, United States
    • ,
  • Sithisat Chiamwongpaet

      Affiliations

    • Bangkok Metropolitan Administration, Bangkok, Thailand
    • ,
  • Udomsak Sangkum

      Affiliations

    • Bangkok Metropolitan Administration, Bangkok, Thailand
    • ,
  • Dwip Kitayaporn

      Affiliations

    • Mahidol University, Bangkok, Thailand
    • Bumrungrad International Hospital, Bangkok, Thailand
    • ,
  • Marc Gurwith

      Affiliations

    • VaxGen, Inc., Brisbane, CA, United States
    • ,
  • Kachit Choopanya

      Affiliations

    • Bangkok Vaccine Evaluation Group, Bangkok, Thailand
    • ,
  • for the Bangkok Vaccine Evaluation Group

      Affiliations

    • The Bangkok Vaccine Evaluation Group—Kachit Choopanya (Principal Investigator), Suphak Vanichseni; The Bangkok Metropolitan Administration (BMA) Department of Health—Sithisat Chiamwongpaet, Wuwanee Raktham, Boonrawd Prasittipol, La-Ong Srisuwanvilai, Kovit Yongvanitjit; BMA Department of Medical Services—Wonchat Subhachaturas, Udomsak Sangkum; Mahidol University—Valai Bussaratid, Jaranit Kaewkungwal, Dwip Kitayaporn, Sricharoen Migasena, Benjaluck Phonrat, Punnee Pitisuttithum, Sawangjai Pungpak, Pravan Suntharasamai; The Thailand Ministry of Public Health—U.S. Centers for Disease Control and Prevention Collaboration—Thanyanan Chaowanachan, Thitima Cherdtrakulkiat, Wanitchaya Kittikraisak, Wanna Leelawiwat, Michael Martin, Janet McNicholl, Supawadee Na-Pompet, Chalintorn Sinthuwattanawibul, Jordan W. Tappero, Frits van Griensven, Punneeporn Wasinrapee, Nancy Young; The U.S. Centers for Disease Control and Prevention—Dale Hu, Timothy D. Mastro; VaxGen, Inc.—Phillip Berman, Lisa Brooks, Marlene Chernow, Don Francis, Carolyn Gee, Marc Gurwith, William Heyward, Tina Ippolito, David Jobes, Tina Kalanon, Elizabeth Li, Aimee Luck, Karin Orelind, Patti Orozco-Cronin, Michael L. Peterson, Faruk Sinangil.

Received 8 October 2009 ,Revised 8 December 2009 ,Accepted 15 December 2009.

References 

  1. Buchacz K, McFarland W, Kellogg TA, Loeb L, Holmberg SD, Dilley J, et al. Amphetamine use is associated with increased HIV incidence among men who have sex with men in San Francisco. AIDS. 2005;19:1423–1424
  2. Centers for Disease Control and Prevention . Methamphetamine use and HIV risk behaviors among heterosexual men—Preliminary results from five northern California counties, December 2001–November 2003. Morbity and Mortality Weekly Report. 2006;55:273–277
  3. Colfax GN, Mansergh G, Guzman R, Vittinghoff E, Marks G, Rader M, et al. Drug use and sexual risk behavior among gay and bisexual men who attend circuit parties: A venue-based comparison. Journal of Acquired Immune Deficiency Syndromes. 2001;28:373–379
  4. Cox DR. Regression models and life-tables. Journal of the Royal Statistical Society. Series B (Methodologica). 1972;34:187–220
  5. Cretzmeyer M, Sarrazin MV, Huber DL, Block RI, Hall JA. Treatment of methamphetamine abuse: Research findings and clinical directions. Journal of Substance Abuse and Treatment. 2003;24:267–277
  6. Diggle PJ, Liang K, Zeger SL. Analysis of longitudinal data. Oxford: Oxford University Press; 1994;
  7. Drumright LN, Little SJ, Strathdee SA, Slymen DJ, Araneta MR, Malcarne VL, et al. Unprotected anal intercourse and substance use among men who have sex with men with recent HIV infection. Journal of Acquired Immune Deficiency Syndromes. 2006;43:344–350
  8. Fairbairn N, Kerr T, Buxton JA, Li K, Montaner JS, Wood E. Increasing use and associated harms of crystal methamphetamine injection in a Canadian setting. Drug and Alcohol Dependence. 2007;88:313–316
  9. Human Rights Watch . Thailand's ‘war on drugs’ International Harm Reduction Association and Human Rights Watch briefing paper. 2008;Retrieved 26 August, 2009 from http://hrw.org/english/docs/2008/03/12/thaila18278.htm
  10. International Herald Tribune . Thailand's crackdown: Drug ‘war’ kills democracy, too. 2003;Retrieved 26 August, 2009 from http://hrw.org/english/docs/2003/04/24/thaila12989.htm (April 24, 2003)
  11. Koblin BA, Husnik MJ, Colfax G, Huang Y, Madison M, Mayer K, et al. Risk factors for HIV infection among men who have sex with men. AIDS. 2006;20:731–739
  12. Konings E, Bantebya G, Caraël M, Bagenda D, Mertens T. Validating population surveys for the measurement of HIV/STD prevention indicators. AIDS. 1995;9:375–382
  13. Patterson TL, Semple SJ, Staines H, Lozada R, Orozovich P, Bucardo J, et al. Prevalence and correlates of HIV infection among female sex workers in 2 Mexico–US border cities. Journal of Infectious Diseases. 2008;197:728–732
  14. Pitisuttithum P, Gilbert P, Gurwith M, Heyward W, Martin M, van Griensven F, et al. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. Journal of Infectious Diseases. 2006;194:1661–1671
  15. Plankey MW, Ostrow DG, Stall R, Cox C, Li X, Peck JA, et al. The relationship between methamphetamine and popper use and risk of HIV seroconversion in the multicenter AIDS cohort study. Journal of Acquired Immune Deficiency Syndromes. 2007;45:85–92
  16. Rawson RA, Marinelli-Casey P, Anglin MD, Dickow A, Frazier Y, Gallagher C, et al. A multi-site comparison of psychosocial approaches for the treatment of methamphetamine dependence. Addiction. 2004;99:708–717
  17. Roche Laboratories, Inc. . Versed (midazolam HCL) injection, package insert. 1999;25419545-0299
  18. Shoptaw S, Reback CJ. Associations between methamphetamine use and HIV among men who have sex with men: A model for guiding public policy. Journal of Urban Health. 2006;83:1151–1157
  19. Shoptaw S, Reback CJ. Methamphetamine use and infectious disease-related behaviors in men who have sex with men: Implications for interventions. Addiction. 2007;102(Suppl. 1):130–135
  20. Suntharasamai P, Martin M, Vanichseni S, van Griensven F, Mock PA, Pitisuttithum P, et al. Factors associated with incarceration and incident HIV infection among injection drug users participating in an HIV vaccine trial in Bangkok, Thailand, 1999–2003. Addiction. 2009;104:235–242
  21. Taylor MM, Aynalem G, Smith LV, Montoya J, Kerndt P. Methamphetamine use and sexual risk behaviours among men who have sex with men diagnosed with early syphilis in Los Angeles County. International Journal STD & AIDS. 2007;18:93–97
  22. Thailand Ministry of Public Health. (2006). HIV/AIDS analytical situation in Thailand (data as of December 31, 2006). AIDS Cluster, Bureau of AIDS, TB and STIs, Department of Diseases Control, Ministry of Public Health, Thailand. Retrieved 26 August, 2009 from http://www.aidsthai.org/aidsenglish/main.php?filename=situation_01.
  23. U.S. Department of Health and Human Services . Substance Abuse and Mental Health Services Administration. Counselor's Treatment Manual—Matrix Intensive Outpatient Treatment for People with Stimulant Use Disorders. 2008;Retrieved 25 August 2009 from http://ncadistore.samhsa.gov/catalog/productDetails.aspx?ProductID=17952
  24. van Griensven F, Keawkungwal J, Tappero JW, Sangkum U, Pitisuttithum P, Vanichseni S, et al. Lack of increased HIV risk behavior among injection drug users participating in the AIDSVAX B/E HIV vaccine trial in Bangkok, Thailand. AIDS. 2004;18:295–301
  25. van Griensven F, Pitisuttithum P, Vanichseni S, Wichienkuer P, Tappero JW, Sangkum U, et al. Trends in the injection of midazolam and other drugs and needle sharing among injection drug users enrolled in the AIDSVAX B/E HIV-1 vaccine trial in Bangkok, Thailand. International Journal of Drug Policy. 2005;16:171–175
  26. Vanichseni S, Kitayaporn D, Mastro TD, Mock PA, Raktham S, Des Jarlais DC, et al. Continued high HIV-1 incidence in a vaccine trial preparatory cohort of injection drug users in Bangkok, Thailand. AIDS. 2001;15:397–405
  27. Vanichseni S, Tappero JW, Pitisuttithum P, Kitayaporn D, Mastro TD, Vimutisunthorn E, et al. Recruitment, screening and characteristics of injection drug users participating in the AIDSVAX B/E HIV vaccine trial, Bangkok, Thailand. AIDS. 2004;18:311–316
  28. Vongchak T, Kawichaia S, Sherman S, Celentano DD, Sirisanthana T, Latkin C, et al. The influence of Thailand's 2003 ‘war on drugs’ policy on self-reported drug use among injection drug users in Chiang Mai, Thailand. International Journal of Drug Policy. 2005;16:115–121
  29. Waldo CR, McFarland W, Katz MH, MacKellar D, Valleroy LA. Very young gay and bisexual men are at risk for HIV infection: The San Francisco Bay Area Young Men's Survey II. Journal of Acquired Immune Deficiency Syndromes. 2000;24:168–174
  30. Weniger BG, Limpakarnjanarat K, Ungchusak K, Thanprasertsuk S, Choopanya K, Vanichseni S, et al. The epidemiology of HIV infection and AIDS in Thailand. AIDS. 1991;5(Suppl. 2):S71–S85
  31. Wohl AR, Johnson DF, Lu S, Jordan W, Beall B, Currier J, et al. HIV risk behaviors among African American men in Los Angeles County who self-identify as heterosexual. Journal of Acquired Immune Deficiency Syndromes. 2002;31:354–360
  32. Woody GE, Donnell D, Seage GR, Metzger D, Marmor M, Koblin BA, et al. Non-injection substance use correlates with risky sex among men having sex with men: Data from HIVNET. Drug Alcohol Dependence. 1999;53:197–205
  33. World Health Organization . WHO, UNODC, UNAIDS technical guide for countries to set targets for universal access to HIV prevention, treatment and care for injecting drug users. 2009;Retrieved 04 December, 2009 from http://www.unodc.org/documents/hiv-aids/WHO%20UNODC%20UNAIDS%20%20IDU%20Universal%20Access%20Target%20Setting%20Guide%20-%20FINAL%20-%20Feb%2009.pdf

☆ Clinical trial registration: The AIDSVAX B/E HIV vaccine trial is registered at ClinicalTrials.gov http://clinicaltrials.gov/ct2/show/NCT00006327?term=AIDSVAX&rank=6 ClinicalTrials.gov Identifier: NCT00006327.

☆☆ Disclaimer: The findings and conclusions in this paper are those of the authors and do not necessarily represent the views of the U.S. Centers for Disease Control and Prevention.

PII: S0955-3959(09)00163-7

doi: 10.1016/j.drugpo.2009.12.002

International Journal of Drug Policy
Volume 21, Issue 4 , Pages 296-301 , July 2010

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