Editors' ChoiceThe effectiveness of compulsory drug treatment: A systematic review
Section snippets
Background
Globally, dependence to illicit and off-label drugs remains a key source of morbidity and mortality, and is implicated in criminal recidivism. For instance, 1.7 million of the world's estimated 13 million people who inject drugs (PWID) are believed to be HIV-positive while more than 60% of PWID globally are estimated to be hepatitis C (HCV) positive (UNODC, 2015). Illicit drug dependence is also estimated to have contribute to 20.0 million disability-adjusted life years in 2010 (Degenhardt,
Methods
We employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for the development of systematic reviews (Moher, Liberati, Tetzlaff, & Altman, 2009). A full review protocol is available by request to the corresponding author.
Study selection and characteristics
Overall, as seen in Fig. 1, 430 studies were initially identified, of which 378 were excluded because they did not present primary and/or specific data on compulsory treatment. Of the remaining 52 studies, 17 were excluded because they constituted reviews or editorials, 18 were excluded because they did not focus on illicit drug use (i.e., they focused on alcohol treatment), and 8 studies were excluded because they evaluated quasi-compulsory treatment rather than compulsory treatment
Summary of evidence
While a limited literature exists, the majority of studies (78%) evaluating compulsory treatment failed to detect any significant positive impacts on drug use or criminal recidivism over other approaches, with two studies (22%) detecting negative impacts of compulsory treatment on criminal recidivism compared with control arms. Further, only two studies (22%) observed a significant impact of long-term compulsory inpatient treatment on criminal recidivism: one reported a small effect size on
Funding
Dan Werb is supported by a US National Institute on Drug Abuse Avenir Award (DP2 DA040256-01) and the Canadian Institutes of Health Research (MOP 79297). Further support was provided by the Open Society Foundations through an operating grant for the International Centre for Science in Drug Policy. This study was also supported by the Canadian Institutes of Health Research through the Canadian Research Initiative in Substance Misuse (SMN–139148 and SMN-139150). Benedikt Fischer acknowledges
Acknowledgments
DW had full access to all the data in the study and had final responsibility for the decision to submit for publication. MM and CR conducted the systematic search, with assistance from DW. DW drafted the manuscript. EW provided guidance on the systematic review and meta-analysis methodology. BF, AK, SS, and EW revised the manuscript substantially. All authors have seen and approved the final version.
Conflict of interest: All authors declare that they have no conflicts of interest.
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